HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	0.60	0.760

Property	Details
Experiments	25168242, 25471832, 30477538, 19619542, 17159902, 17170702, 17268548, 17568776, 18309296, 18566590, 19536131, 17139261, 17290220, 19798103, 18388957, 19098711
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002020 - protease binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 685
+	Hs
		175814 P73_HUMAN (13-362): 2.35e-166: 481: 39.74		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		386475 P53_HUMAN (1-393): 0: 619: 100.00		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Hs
		171471 P53_HUMAN (1-393): 0: 619: 100.00		UBD_HUMAN (155-304): 5.41e-28: 112: 32.05
+	Hs
		385966 P53_HUMAN (1-393): 0: 619: 100.00		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Rn
		488473 P53_RAT (1-393): 0: 572: 77.02		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		398093 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69