Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Interactor 2: BCL2 (P10415)
Apoptosis regulator Bcl-2
Gene: BCL2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 23316052, 16443602, 30683842, 32064756, 21624955, 21597459, 19521340, 12667443 |
| Identification Methods | x-ray crystallography, biochemical, pull down, affinity chromatography technology, unspecified method, anti bait coimmunoprecipitation |
| Interaction Type | association, direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~P53, BH4~P53 |
| Common GO terms | GO:0001836 - release of cytochrome c from mitochondria GO:0002020 - protease binding GO:0002326 - B cell lineage commitment GO:0002931 - response to ischemia GO:0005634 - nucleus and 21 others more... |
| Homologous interactions | 9 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
