HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: PRS6A (P17980)
26S proteasome regulatory subunit 6A (26S proteasome AAA-ATPase subunit RPT5) (Proteasome 26S subunit ATPase 3) (Proteasome subunit P50) (Tat-binding protein 1) (TBP-1)
Gene: PSMC3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20479273
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 439
+	Hs
		386441 P53_HUMAN (1-393): 0: 619: 100.00		PRS4_HUMAN (32-433): 5.45e-136: 399: 43.60
+	Hs
		386442 P53_HUMAN (1-393): 0: 619: 100.00		PRS8_HUMAN (65-437): 1.93e-126: 373: 44.39
+	Hs
		386267 P53_HUMAN (1-393): 0: 619: 100.00		PRS6B_HUMAN (8-438): 1.04e-118: 354: 37.59
+	Hs
		386385 P53_HUMAN (1-393): 0: 619: 100.00		TERA_HUMAN (162-434): 9.21e-77: 256: 35.17
+	Hs
		875309 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		TERA_HUMAN (162-434): 9.21e-77: 256: 35.17
+	Dm
		820498 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		PRS4_DROME (5-433): 2.8e-136: 400: 42.49