HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 8083962, 10601022, 11313951, 12379483, 8405994, 8395834, 1465435, 10359315, 7799929, 9349482
Identification Methods pull down, affinity chromatography technology, far western blotting
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001046 - core promoter sequence-specific DNA binding
GO:0005634 - nucleus
and 4 others

more...
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 393
Hs

1 339
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024