HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.55	0.614

The method score is based on:

Property	Details
Experiments	10823891, 32814053
Identification Methods	pull down, affinity chromatography technology, validated two hybrid, two hybrid array, two hybrid pooling approach, biochemical
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005783 - endoplasmic reticulum and 3 others more... GO:0005829 - cytosol GO:0032991 - protein-containing complex GO:0043065 - positive regulation of apoptotic process
Homologous interactions	0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024