HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: BRCC3 (P46736)
Lys-63-specific deubiquitinase BRCC36 (EC 3.4.19.-) (BRCA1-A complex subunit BRCC36) (BRCA1/BRCA2-containing complex subunit 3) (BRCA1/BRCA2-containing complex subunit 36) (BRISC complex subunit BRCC36)
Gene: BRCC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 0.60 0.606

The method score is based on:

Property Details
Experiments 14636569, 27229929
Identification Methods affinity chromatography technology, biochemical, two hybrid pooling approach
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006302 - double-strand break repair
and 2 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 393
Hs

1 316
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024