HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.727

Property	Details
Experiments	16169070, 25144556, 31152661, 35140242, 23443559, 22653443
Identification Methods	two hybrid, affinity chromatography technology, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003730 - mRNA 3'-UTR binding GO:0005813 - centrosome GO:0005829 - cytosol GO:0050821 - protein stabilization
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 541
+	Hs
		386306 P53_HUMAN (1-393): 0: 619: 100.00		TCPG_HUMAN (14-540): 0: 572: 33.15
+	Hs
		387386 P53_HUMAN (1-393): 0: 619: 100.00		TCPH_HUMAN (12-539): 0: 570: 29.64
+	Hs
		386057 P53_HUMAN (1-393): 0: 619: 100.00		TCPA_HUMAN (26-541): 0: 545: 32.08
+	Hs
		386337 P53_HUMAN (1-393): 0: 619: 100.00		TCPD_HUMAN (36-533): 1.62e-107: 333: 39.80