HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: NEST (P48681)
Nestin
Gene: NES

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35474131
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0051402 - neuron apoptotic process GO:0072089 - stem cell proliferation
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1621
+	Hs
		385920 P53_HUMAN (1-393): 0: 619: 100.00		K2C8_HUMAN (7-315): 1.79e-122: 395: 23.68
+	Hs
		385950 P53_HUMAN (1-393): 0: 619: 100.00		VIME_HUMAN (8-343): 3.05e-118: 382: 28.32
+	Hs
		386010 P53_HUMAN (1-393): 0: 619: 100.00		K2C5_HUMAN (7-319): 3.83e-86: 296: 20.56
+	Hs
		380435 P53_HUMAN (1-393): 0: 619: 100.00		K2C6B_HUMAN (6-332): 2.95e-86: 295: 21.11
+	Hs
		387710 P53_HUMAN (1-393): 0: 619: 100.00		MYH13_HUMAN (549-1526): 1.29e-30: 134: 10.01
+	Hs
		386212 P53_HUMAN (1-393): 0: 619: 100.00		MYH9_HUMAN (729-1459): 1.22e-24: 115: 10.48
+	Hs
		387815 P53_HUMAN (1-393): 0: 619: 100.00		MYH4_HUMAN (17-755): 1.14e-23: 111: 10.41
+	Hs
		531632 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		K2C5_HUMAN (7-319): 3.83e-86: 296: 20.56
+	Hs
		821689 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		K2C6C_HUMAN (6-329): 1.25e-86: 296: 21.30
+	Hs
		386014 P53_HUMAN (1-393): 0: 619: 100.00		GFAP_HUMAN (8-316): 8.2e-22: 102: 30.35
+	Hs
		1034623 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		GOGA4_HUMAN (1-602): 3.69e-15: 83.8: 9.31