Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: BRCA2 (P51587)
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
Gene: BRCA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.55 0.707

The method score is based on:

Property Details
Experiments 14636569, 20421506, 9811893, 32807901, 34795231, 38580884
Identification Methods affinity chromatography technology, biochemical, pull down, proximity labelling technology, isothermal titration calorimetry, nuclear magnetic resonance, coimmunoprecipitation, classical fluorescence spectroscopy
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002020 - protease binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
and 11 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024