HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: UBE2N (P61088)
Ubiquitin-conjugating enzyme E2 N (EC 2.3.2.23) (Bendless-like ubiquitin-conjugating enzyme) (E2 ubiquitin-conjugating enzyme N) (Ubc13) (UbcH13) (Ubiquitin carrier protein N) (Ubiquitin-protein ligase N)
Gene: UBE2N

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	17000756, 19651615
Identification Methods	pull down, affinity chromatography technology, enzymatic study
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 152
+	Hs
		386463 P53_HUMAN (1-393): 0: 619: 100.00		UB2D2_HUMAN (4-149): 9.96e-80: 233: 46.58
+	Hs
		386309 P53_HUMAN (1-393): 0: 619: 100.00		UBE2A_HUMAN (1-146): 5.35e-70: 209: 39.46
+	Hs
		386483 P53_HUMAN (1-393): 0: 619: 100.00		UBE2B_HUMAN (1-146): 2.71e-69: 207: 39.46
+	Mm
		356834 P53_MOUSE (1-393): 0: 589: 77.35		UBE2N_MOUSE (1-152): 1.51e-73: 218: 100.00
+	Dr
		945418 P53_DANRE (85-393): 2.15e-154: 441: 56.83		Q7T3F3_DANRE (1-152): 7.7e-72: 214: 97.37
+	Dm
		627011 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		UBCD6_DROME (1-146): 2.87e-72: 215: 40.82