HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 11751391, 35474131, 9744860, 25362358, 10608806, 10601022, 8940078, 12756247, 9679063, 19918261, 9363941, 10713094
Identification Methods affinity chromatography technology, enzymatic study, unspecified method
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0001756 - somitogenesis
GO:0002326 - B cell lineage commitment
GO:0002360 - T cell lineage commitment
GO:0005634 - nucleus
and 15 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 393
Hs

1 4128
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024