Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.984 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24474649, 26556313, 30683842, 32064756, 20837658, 25115399, 21900206, 24814347, 12667443, 14963330, 16151013 |
| Identification Methods | affinity chromatography technology, pull down, two hybrid, anti bait coimmunoprecipitation, nuclear magnetic resonance, anti tag coimmunoprecipitation, fluorescence polarization spectroscopy, isothermal titration calorimetry, surface plasmon resonance |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~P53, BH4~P53 |
| Common GO terms | GO:0001701 - in utero embryonic development GO:0001836 - release of cytochrome c from mitochondria GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix and 7 others more... |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
