Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Interactor 2: TP53B (Q12888)
TP53-binding protein 1 (53BP1) (p53-binding protein 1) (p53BP1)
Gene: TP53BP1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.989 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27546791, 25651062, 15364958, 15611139, 33606978, 8016121, 26022179, 12110597, 14978302, 11877378, 12351827, 38580884, 20307547, 22084066, 25579814, 25837623, 17805299, 19433796, 34591642, 22653443 |
| Identification Methods | affinity chromatography technology, x-ray crystallography, unspecified method, pull down, two hybrid, proximity labelling technology, nuclear magnetic resonance, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, classical fluorescence spectroscopy and 1 others
more... |
| Interaction Type | physical association, association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BRCT_3~P53 |
| Common GO terms | GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005657 - replication fork GO:0005737 - cytoplasm and 5 others more... |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Xl | |
 |
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
