Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: MP2K5 (Q13163)
Dual specificity mitogen-activated protein kinase kinase 5 (MAP kinase kinase 5) (MAPKK 5) (EC 2.7.12.2) (MAPK/ERK kinase 5) (MEK 5)
Gene: MAP2K5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.501

The method score is based on:

Property Details
Experiments 28205554
Identification Methods fluorescent resonance energy transfer
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 393
Hs

1 448
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024