Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: ATM (Q13315)
Serine-protein kinase ATM (EC 2.7.11.1) (Ataxia telangiectasia mutated) (A-T mutated)
Gene: ATM

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 15713674, 22893124, 25086746, 24469230, 14744854, 15632067, 15159397, 9843217, 10608806, 20010693, 23890999, 23525106, 12645530, 30089259, 16221684, 15064416, 17409407, 11459832, 21383020, 19965871 and 5 others

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Identification Methods pull down, affinity chromatography technology, enzymatic study, unspecified method, in-gel kinase assay, experimental interaction detection
Interaction Type direct interaction, physical association, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001756 - somitogenesis
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
and 19 others

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Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 393
Hs

1 3056
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024