HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TRI29 (Q14134)
Tripartite motif-containing protein 29 (Ataxia telangiectasia group D-associated protein)
Gene: TRIM29

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20368352
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0002039 - p53 binding GO:0008270 - zinc ion binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 588
+	Hs
		386071 P53_HUMAN (1-393): 0: 619: 100.00		RO52_HUMAN (140-588): 2.7e-92: 293: 16.74
+	Hs
		387532 P53_HUMAN (1-393): 0: 619: 100.00		TRI45_HUMAN (37-515): 4.44e-81: 267: 12.92
+	Hs
		262148 P53_HUMAN (1-393): 0: 619: 100.00		TRIM3_HUMAN (136-566): 5.8e-77: 260: 15.75
+	Hs
		387560 P53_HUMAN (1-393): 0: 619: 100.00		TRI39_HUMAN (148-531): 5.93e-79: 260: 14.75
+	Hs
		386017 P53_HUMAN (1-393): 0: 619: 100.00		TRI27_HUMAN (140-503): 7.63e-79: 259: 14.42
+	Hs
		387458 P53_HUMAN (1-393): 0: 619: 100.00		TRIM2_HUMAN (141-566): 1.22e-74: 254: 15.05
+	Hs
		387455 P53_HUMAN (1-393): 0: 619: 100.00		TRIM8_HUMAN (171-531): 3.4e-66: 227: 18.43
+	Hs
		386725 P53_HUMAN (1-393): 0: 619: 100.00		TRI25_HUMAN (104-416): 2.68e-62: 218: 24.68
+	Hs
		387317 P53_HUMAN (1-393): 0: 619: 100.00		TRI47_HUMAN (131-376): 7.87e-54: 195: 27.94
+	Hs
		386945 P53_HUMAN (1-393): 0: 619: 100.00		TRI65_HUMAN (168-384): 3.48e-47: 174: 23.51
+	Hs
		387186 P53_HUMAN (1-393): 0: 619: 100.00		TRI41_HUMAN (182-393): 5.56e-42: 162: 22.07