Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: CUL7 (Q14999)
Cullin-7 (CUL-7)
Gene: CUL7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 24711643, 31343991, 35982156, 16547496, 17229476, 17332328, 17942889, 17298945, 16875676, 26186194, 25609649, 28514442, 25003318, 31152661, 31570706, 33961781, 35140242, 34591612, 38580884, 23443559 and 2 others

more...

Identification Methods affinity chromatography technology, enzymatic study, two hybrid, pull down, proximity labelling technology, nuclear magnetic resonance, tandem affinity purification, molecular sieving, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 393
Hs

1 1698
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024