HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: SAFB1 (Q15424)
Scaffold attachment factor B1 (SAF-B) (SAF-B1) (HSP27 estrogen response element-TATA box-binding protein) (HSP27 ERE-TATA-binding protein)
Gene: SAFB

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.534

Property	Details
Experiments	21130767
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 915
+	Hs
		386717 P53_HUMAN (1-393): 0: 619: 100.00		SAFB2_HUMAN (1-906): 1.05e-88: 305: 68.34
+	Hs
		387274 P53_HUMAN (1-393): 0: 619: 100.00		MSI2H_HUMAN (297-559): 1.06e-53: 191: 14.34
+	Hs
		1073560 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		SAFB1_HUMAN (1-915): 3.38e-116: 378: 100.00
+	Hs
		386661 P53_HUMAN (1-393): 0: 619: 100.00		PABP4_HUMAN (258-499): 1.89e-40: 161: 15.29
+	Hs
		387500 P53_HUMAN (1-393): 0: 619: 100.00		PABP3_HUMAN (258-583): 1.86e-38: 154: 11.21
+	Hs
		385994 P53_HUMAN (1-393): 0: 619: 100.00		PABP1_HUMAN (258-499): 7.93e-38: 153: 14.51