HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: UB2V2 (Q15819)
Ubiquitin-conjugating enzyme E2 variant 2 (DDVit 1) (Enterocyte differentiation-associated factor 1) (EDAF-1) (Enterocyte differentiation-promoting factor 1) (EDPF-1) (MMS2 homolog) (Vitamin D3-inducible protein)
Gene: UBE2V2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	27229929
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 145
+	Hs
		386463 P53_HUMAN (1-393): 0: 619: 100.00		UB2D2_HUMAN (10-144): 3.07e-58: 179: 22.06
+	Hs
		386309 P53_HUMAN (1-393): 0: 619: 100.00		UBE2A_HUMAN (7-144): 6.23e-58: 178: 21.58
+	Hs
		386483 P53_HUMAN (1-393): 0: 619: 100.00		UBE2B_HUMAN (7-144): 2.17e-57: 177: 20.86
+	Hs
		386492 P53_HUMAN (1-393): 0: 619: 100.00		UBC9_HUMAN (7-143): 1.02e-54: 170: 21.01
+	Hs
		930260 Q5U0E4_HUMAN (1-393): 0: 612: 99.49		UBC9_HUMAN (7-143): 1.02e-54: 170: 21.01
+	Hs
		175854 P73_HUMAN (13-362): 2.35e-166: 481: 39.74		UBC9_HUMAN (7-143): 1.02e-54: 170: 21.01
+	Hs
		930389 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		UBC9_HUMAN (7-143): 1.02e-54: 170: 21.01
+	Dm
		627011 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		UBCD6_DROME (7-144): 1.52e-58: 180: 22.30