HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: TAF9 (Q16594)
Transcription initiation factor TFIID subunit 9 (RNA polymerase II TBP-associated factor subunit G) (STAF31/32) (Transcription initiation factor TFIID 31 kDa subunit) (TAFII-31) (TAFII31) (Transcription initiation factor TFIID 32 kDa subunit) (TAFII-32) (TAFII32)
Gene: TAF9

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.741

The method score is based on:

Property	Details
Experiments	26282181, 10601022, 7761466, 38580884, 18250150, 11278372, 7809597
Identification Methods	pull down, affinity chromatography technology, proximity labelling technology, coimmunoprecipitation, molecular sieving
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000976 - transcription cis-regulatory region binding GO:0002039 - p53 binding GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 8 others more... GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0006974 - DNA damage response GO:0043066 - negative regulation of apoptotic process GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046982 - protein heterodimerization activity GO:0050821 - protein stabilization
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	393
Hs

1	264

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024