Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: IF16 (Q16666)
Gamma-interferon-inducible protein 16 (Ifi-16) (Interferon-inducible myeloid differentiation transcriptional activator)
Gene: IFI16

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.679

The method score is based on:

Property Details
Experiments 30193098, 11146555, 21397192
Identification Methods affinity chromatography technology, pull down, classical fluorescence spectroscopy, anti bait coimmunoprecipitation, confocal microscopy
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
and 8 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 393
Hs

1 785
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024