HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: FILA2 (Q5D862)
Filaggrin-2 (FLG-2) (Intermediate filament-associated and psoriasis-susceptibility protein) (Ifapsoriasin)
Gene: FLG2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35474131
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	S_100~TAD2
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 2391
+	Hs
		387646 P53_HUMAN (1-393): 0: 619: 100.00		CHD7_HUMAN (1784-2314): 2.13e-81: 302: 11.99
+	Hs
		386104 P53_HUMAN (1-393): 0: 619: 100.00		S10A1_HUMAN (2-93): 2.13e-45: 161: 36.96
+	Hs
		380714 P53_HUMAN (1-393): 0: 619: 100.00		S100B_HUMAN (1-92): 2.49e-44: 158: 36.96
+	Hs
		386132 P53_HUMAN (1-393): 0: 619: 100.00		S100P_HUMAN (1-95): 1.9e-43: 155: 41.05
+	Hs
		386185 P53_HUMAN (1-393): 0: 619: 100.00		S10AB_HUMAN (2-102): 3.2e-43: 155: 39.60
+	Hs
		386137 P53_HUMAN (1-393): 0: 619: 100.00		S10A4_HUMAN (3-101): 5.85e-41: 148: 29.29
+	Hs
		386512 P53_HUMAN (1-393): 0: 619: 100.00		S10AC_HUMAN (1-92): 1.61e-40: 147: 36.96
+	Hs
		386155 P53_HUMAN (1-393): 0: 619: 100.00		S10A2_HUMAN (2-91): 8.89e-40: 145: 32.22
+	Hs
		386412 P53_HUMAN (1-393): 0: 619: 100.00		S10AA_HUMAN (2-89): 2.76e-39: 143: 34.09
+	Hs
		385910 P53_HUMAN (1-393): 0: 619: 100.00		S10A8_HUMAN (1-95): 8.99e-36: 133: 29.47
+	Hs
		386191 P53_HUMAN (1-393): 0: 619: 100.00		S10A5_HUMAN (2-93): 7.39e-36: 133: 33.70
+	Hs
		385924 P53_HUMAN (1-393): 0: 619: 100.00		S10A6_HUMAN (4-90): 3.33e-27: 109: 31.03
+	Hs
		386192 P53_HUMAN (1-393): 0: 619: 100.00		S10A3_HUMAN (4-98): 1.25e-21: 93.6: 26.32
+	Hs
		387371 P53_HUMAN (1-393): 0: 619: 100.00		S10AD_HUMAN (1-83): 5.04e-20: 89: 32.53
+	Hs
		387288 P53_HUMAN (1-393): 0: 619: 100.00		S10AG_HUMAN (2-97): 4.33e-19: 86.3: 28.87
+	Hs
		387043 P53_HUMAN (1-393): 0: 619: 100.00		HORN_HUMAN (1590-2390): 3.13e-13: 78: 17.93
+	Hs
		146135 P53_HUMAN (1-393): 0: 619: 100.00		ARI1A_HUMAN (169-1510): 1.82e-12: 75.5: 10.31