HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: RN187 (Q5TA31)
E3 ubiquitin-protein ligase RNF187 (EC 2.3.2.27) (RING domain AP1 coactivator 1) (RACO-1) (RING finger protein 187) (RING-type E3 ubiquitin transferase RNF187)
Gene: RNF187

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	35165289
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 235
+	Hs
		387560 P53_HUMAN (1-393): 0: 619: 100.00		TRI39_HUMAN (3-235): 4.5e-56: 188: 24.79
+	Hs
		386629 P53_HUMAN (1-393): 0: 619: 100.00		TRI26_HUMAN (3-235): 1.27e-53: 182: 20.00
+	Hs
		386071 P53_HUMAN (1-393): 0: 619: 100.00		RO52_HUMAN (3-235): 1.81e-53: 180: 23.14
+	Hs
		386017 P53_HUMAN (1-393): 0: 619: 100.00		TRI27_HUMAN (4-235): 1.26e-50: 173: 20.58
+	Hs
		387456 P53_HUMAN (1-393): 0: 619: 100.00		TRI31_HUMAN (3-235): 7.42e-45: 156: 17.28
+	Hs
		387032 P53_HUMAN (1-393): 0: 619: 100.00		TRI69_HUMAN (1-235): 2.59e-43: 154: 18.11
+	Hs
		262148 P53_HUMAN (1-393): 0: 619: 100.00		TRIM3_HUMAN (10-227): 8.76e-42: 152: 12.97