HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: ZN679 (Q8IYX0)
Zinc finger protein 679
Gene: ZNF679

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	27229929
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 411
+	Hs
		387152 P53_HUMAN (1-393): 0: 619: 100.00		ZN420_HUMAN (42-394): 7.1e-161: 470: 41.97
+	Hs
		387667 P53_HUMAN (1-393): 0: 619: 100.00		ZN629_HUMAN (42-404): 5.97e-74: 249: 19.06
+	Hs
		387691 P53_HUMAN (1-393): 0: 619: 100.00		ZN180_HUMAN (42-187): 1.1e-44: 166: 13.51
+	Hs
		386574 P53_HUMAN (1-393): 0: 619: 100.00		ZNF92_HUMAN (42-147): 3.01e-16: 82.7: 5.56
+	Hs
		1237208 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		ZN676_HUMAN (151-379): 4.62e-81: 261: 64.19