Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.94 | 0.60 | 0.754 |
The method score is based on:
Property | Details |
---|---|
Experiments | 27534417, 29379285, 36650277, 16931761, 15103385, 21625211, 23736031 |
Identification Methods | affinity chromatography technology, pull down, enzymatic study, x-ray crystallography, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, experimental interaction detection |
Interaction Type | physical association, direct interaction, association, ubiquitination reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | - |
Common GO terms | GO:0005654 - nucleoplasm GO:0005829 - cytosol |
Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024