Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.754

The method score is based on:

Property Details
Experiments 27534417, 29379285, 36650277, 16931761, 15103385, 21625211, 23736031
Identification Methods affinity chromatography technology, pull down, enzymatic study, x-ray crystallography, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type physical association, direct interaction, association, ubiquitination reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 393
Hs

1 731
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024