Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: BBC3B (Q96PG8)
Bcl-2-binding component 3, isoforms 3/4 (JFY-1) (p53 up-regulated modulator of apoptosis)
Gene: BBC3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.55 0.559

The method score is based on:

Property Details
Experiments 16990795, 18443131
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005739 - mitochondrion
GO:0070059 - intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0090200 - positive regulation of release of cytochrome c from mitochondria
GO:2001244 - positive regulation of intrinsic apoptotic signaling pathway
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024