Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53
Interactor 2: NOTC4 (Q99466)
Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain]
Gene: NOTCH4
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 21402876 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~P53 |
| Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000987 - cis-regulatory region sequence-specific DNA binding GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0005654 - nucleoplasm and 3 others more... |
| Homologous interactions | 7 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
