HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: MEP50 (Q9BQA1)
Methylosome protein WDR77 (Androgen receptor cofactor p44) (Methylosome protein 50) (MEP-50) (WD repeat-containing protein 77) (p44/Mep50)
Gene: WDR77

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25144556
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 342
+	Hs
		387464 P53_HUMAN (1-393): 0: 619: 100.00		WDR33_HUMAN (58-331): 3.52e-67: 230: 17.86
+	Hs
		386213 P53_HUMAN (1-393): 0: 619: 100.00		COPB2_HUMAN (54-331): 3.17e-47: 172: 18.38
+	Hs
		387246 P53_HUMAN (1-393): 0: 619: 100.00		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29
+	Hs
		386793 P53_HUMAN (1-393): 0: 619: 100.00		TAF5_HUMAN (178-328): 1.2e-21: 98: 18.42
+	Hs
		386436 P53_HUMAN (1-393): 0: 619: 100.00		WDR5_HUMAN (247-341): 5.14e-19: 88.2: 19.79
+	Hs
		1281386 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		FBXW7_HUMAN (3-236): 5.23e-43: 159: 14.29