Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: ANKR2 (Q9GZV1)
Ankyrin repeat domain-containing protein 2 (Skeletal muscle ankyrin repeat protein) (hArpp)
Gene: ANKRD2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 15136035
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~P53
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
and 3 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 393
Hs

1 360
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024