HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: HIPK2 (Q9H2X6)
Homeodomain-interacting protein kinase 2 (hHIPk2) (EC 2.7.11.1)
Gene: HIPK2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.760

The method score is based on:

Property Details
Experiments 25961923, 11740489, 11925430, 22893124, 38580884, 21057547, 16212962, 25313037, 22110707, 34133717, 15896780, 17349959
Identification Methods pull down, affinity chromatography technology, two hybrid, proximity labelling technology, enzymatic study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0007179 - transforming growth factor beta receptor signaling pathway
and 9 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 393
Hs

1 1198
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024