HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: KAT8 (Q9H7Z6)
Histone acetyltransferase KAT8 (EC 2.3.1.48) (Lysine acetyltransferase 8) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1) (MYST-1) (Males-absent on the first protein homolog) (hMOF) (Protein acetyltransferase KAT8) (EC 2.3.1.-) (Protein propionyltransferase KAT8) (EC 2.3.1.-)
Gene: KAT8

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.688

The method score is based on:

Property	Details
Experiments	17189187, 19854137, 15960975, 16601686
Identification Methods	enzymatic study, pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005739 - mitochondrion GO:0006357 - regulation of transcription by RNA polymerase II and 6 others more... GO:0016363 - nuclear matrix GO:0019899 - enzyme binding GO:0045815 - transcription initiation-coupled chromatin remodeling GO:0045892 - negative regulation of DNA-templated transcription GO:0045893 - positive regulation of DNA-templated transcription GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	393
Hs

1	458

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024