HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: RNC (Q9NRR4)
Ribonuclease 3 (EC 3.1.26.3) (Protein Drosha) (Ribonuclease III) (RNase III) (p241)
Gene: DROSHA

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	38580884, 19626115, 24219989
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005829 - cytosol GO:0010628 - positive regulation of gene expression
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 1374
+	Hs
		387536 P53_HUMAN (1-393): 0: 619: 100.00		UBP42_HUMAN (10-498): 9.62e-37: 153: 16.08
+	Hs
		123829 P53_HUMAN (1-393): 0: 619: 100.00		SPT5H_HUMAN (16-221): 2.94e-16: 86.9: 19.54
+	Hs
		387139 P53_HUMAN (1-393): 0: 619: 100.00		KMT2C_HUMAN (4-535): 5.86e-12: 73: 12.54