HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: WWOX (Q9NZC7)
WW domain-containing oxidoreductase (EC 1.1.1.-) (Fragile site FRA16D oxidoreductase) (Short chain dehydrogenase/reductase family 41C member 1)
Gene: WWOX

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.701

The method score is based on:

Property	Details
Experiments	11058590, 16219768, 31315632, 15580310
Identification Methods	two hybrid, affinity chromatography technology, fluorescent resonance energy transfer, anti bait coimmunoprecipitation
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0019899 - enzyme binding and 2 others more... GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0072332 - intrinsic apoptotic signaling pathway by p53 class mediator
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1	393
Hs

1	414

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024