HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	32807901, 20308539, 23443559
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003730 - mRNA 3'-UTR binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 577
+	Hs
		127981 P53_HUMAN (1-393): 0: 619: 100.00		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		175931 P73_HUMAN (13-362): 2.35e-166: 481: 39.74		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		1330005 P63_HUMAN (28-363): 2.35e-145: 429: 42.11		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		387257 P53_HUMAN (1-393): 0: 619: 100.00		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		387237 P53_HUMAN (1-393): 0: 619: 100.00		FUBP2_HUMAN (118-416): 2.4e-14: 78.1: 15.89
+	Hs
		386781 P53_HUMAN (1-393): 0: 619: 100.00		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Dm
		112944 Q9N6D8_DROME (124-325): 3.11e-77: 245: 24.31		M9NF14_DROME (460-571): 2.3e-09: 62.3: 20.18