HitPredict

Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: MAGC2 (Q9UBF1)
Melanoma-associated antigen C2 (Cancer/testis antigen 10) (CT10) (Hepatocellular carcinoma-associated antigen 587) (MAGE-C2 antigen) (MAGE-E1 antigen)
Gene: MAGEC2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20864041
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding and 1 others more... GO:0042826 - histone deacetylase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 393 Hs			1 373
+	Hs
		387319 P53_HUMAN (1-393): 0: 619: 100.00		MAGBI_HUMAN (1-373): 4.06e-119: 350: 37.93
+	Hs
		386265 P53_HUMAN (1-393): 0: 619: 100.00		MAGA2_HUMAN (1-342): 4.66e-111: 328: 36.89
+	Hs
		386264 P53_HUMAN (1-393): 0: 619: 100.00		MAGA1_HUMAN (35-331): 1.83e-110: 327: 43.05
+	Hs
		387741 P53_HUMAN (1-393): 0: 619: 100.00		MAGD2_HUMAN (1-337): 9.5e-107: 327: 27.35
+	Hs
		180193 P53_HUMAN (1-393): 0: 619: 100.00		MAGB2_HUMAN (61-342): 3.21e-106: 316: 43.60
+	Hs
		387373 P53_HUMAN (1-393): 0: 619: 100.00		NECD_HUMAN (50-358): 1.07e-97: 294: 28.21
+	Mm
		356825 P53_MOUSE (1-393): 0: 589: 77.35		NECD_MOUSE (50-358): 5.74e-102: 306: 26.94
+	Hs
		175839 P73_HUMAN (13-362): 2.35e-166: 481: 39.74		MAGA2_HUMAN (1-342): 4.66e-111: 328: 36.89