Interactor 1: P53 (P04637)
Cellular tumor antigen p53 (Antigen NY-CO-13) (Phosphoprotein p53) (Tumor suppressor p53)
Gene: TP53

Interactor 2: DAXX (Q9UER7)
Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)
Gene: DAXX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.763

The method score is based on:

Property Details
Experiments 27626385, 38580884, 12954772, 12482984, 21482821, 15364927, 15339933, 23038753, 28875283, 32545337, 16845383, 21134643
Identification Methods pull down, proximity labelling technology, two hybrid, affinity chromatography technology, unspecified method, nuclear magnetic resonance, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002039 - p53 binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 393
Hs

1 740
+ Mm
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024