HitPredict

Interactor 1: TOP1 (P04786)
DNA topoisomerase 1 (EC 5.6.2.1) (DNA topoisomerase I) (Maintenance of killer protein 1)
Gene: TOP1

Interactor 2: SPT16 (P32558)
FACT complex subunit SPT16 (Cell division control protein 68) (Facilitates chromatin transcription complex subunit SPT16) (Suppressor of Ty protein 16)
Gene: SPT16

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	11805837, 16554755, 37968396
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006325 - chromatin organization GO:0006368 - transcription elongation by RNA polymerase II GO:0031298 - replication fork protection complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 769 Sc			1 1035
+	Hs
		508790 TOP1_HUMAN (643-769): 2.16e-36: 148: 38.28		SP16H_HUMAN (4-1028): 0: 1082: 32.76