HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 25277244, 28130664, 30385828, 32417755, 22365833, 10383393, 11003656, 15581903, 25036637
Identification Methods two hybrid, pull down, cosedimentation in solution, reverse ras recruitment system, luminescence based mammalian interactome mapping
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HSP20~HSP20
Common GO terms GO:0000502 - proteasome complex
GO:0001533 - cornified envelope
GO:0001932 - regulation of protein phosphorylation
GO:0003723 - RNA binding
GO:0005080 - protein kinase C binding
and 38 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 205
Hs

1 205
+ Mm
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Bt
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024