HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: ADT3 (P12236)
ADP/ATP translocase 3 (ADP,ATP carrier protein 3) (ADP,ATP carrier protein, isoform T2) (ANT 2) (Adenine nucleotide translocator 3) (ANT 3) (Solute carrier family 25 member 6) [Cleaved into: ADP/ATP translocase 3, N-terminally processed]
Gene: SLC25A6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30669930
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 298
+	Hs
		388147 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		ADT2_HUMAN (1-297): 8.7e-111: 324: 92.26
+	Hs
		358964 CRYAB_HUMAN (18-197): 6.14e-51: 164: 39.44		ADT3_HUMAN (1-298): 7.29e-113: 329: 100.00
+	Mm
		851107 HSPB2_MOUSE (1-181): 3.51e-43: 144: 33.88		ADT2_MOUSE (1-297): 3.08e-111: 325: 91.25
+	Hs
		388786 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		S2513_HUMAN (3-271): 4.13e-43: 158: 18.96
+	Hs
		358793 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		SCMC2_HUMAN (3-199): 3.97e-45: 160: 23.35
+	Hs
		274469 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		S2512_HUMAN (12-119): 3.18e-19: 89.5: 22.02
+	Mm
		1206508 HSPB2_MOUSE (1-181): 3.51e-43: 144: 33.88		S2512_MOUSE (12-119): 1.84e-19: 90.2: 22.94
+	Dm
		359127 HSP23_DROME (32-203): 9.47e-48: 156: 29.55		ADT_DROME (200-297): 7.46e-12: 66.7: 25.74
+	Dm
		248272 HSP23_DROME (32-203): 9.47e-48: 156: 29.55		O62526_DROME (4-99): 7.37e-10: 60.6: 25.00