HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	0.60	0.729

Property	Details
Experiments	26627832, 26618866, 31324722, 23155000, 17110338, 29924966
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 1480
+	Hs
		529174 HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529884 HSPB8_HUMAN (1-180): 1.08e-42: 143: 37.17		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		238940 HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52		ABCC9_HUMAN (1213-1430): 7.34e-10: 66.2: 23.71