HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	25796446, 27684187
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 504
+	Hs
		125080 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		388717 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42
+	Hs
		388735 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		SMUF2_HUMAN (99-504): 4.95e-107: 337: 19.19
+	Hs
		359059 CRYAB_HUMAN (18-197): 6.14e-51: 164: 39.44		NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73
+	Hs
		388768 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61
+	Hs
		358791 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		WWC2_HUMAN (163-315): 3.48e-35: 142: 24.18
+	Hs
		358913 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61
+	Hs
		1080911 HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61