HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: SQSTM (Q13501)
Sequestosome-1 (EBI3-associated protein of 60 kDa) (EBIAP) (p60) (Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa) (Ubiquitin-binding protein p62)
Gene: SQSTM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.614

The method score is based on:

Property Details
Experiments 25277244, 30669930
Identification Methods two hybrid, affinity chromatography technology, reverse ras recruitment system
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005080 - protein kinase C binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0019901 - protein kinase binding
GO:0035556 - intracellular signal transduction
and 3 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 205
Hs

1 440
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024