HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: ACAP2 (Q15057)
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 (Centaurin-beta-2) (Cnt-b2)
Gene: ACAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	25277244
Identification Methods	two hybrid, reverse ras recruitment system
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 778
+	Hs
		388790 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		DP13A_HUMAN (4-433): 6.2e-68: 239: 20.09
+	Hs
		358834 CRYAA_HUMAN (21-195): 8.38e-54: 171: 38.42		DP13B_HUMAN (4-370): 2.6e-70: 245: 24.02
+	Hs
		388207 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		ANK1_HUMAN (418-726): 3.77e-32: 137: 17.69
+	Hs
		63193 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		AGAP5_HUMAN (330-513): 7.25e-30: 128: 40.32
+	Hs
		388503 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		AGAP9_HUMAN (330-513): 1.35e-27: 121: 38.71
+	Hs
		388666 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		AGAP4_HUMAN (567-697): 5.76e-14: 77.6: 25.37
+	Hs
		388504 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		AGAP7_HUMAN (601-697): 1.74e-13: 76: 29.29
+	Hs
		388665 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		AGAP3_HUMAN (607-697): 5.24e-12: 71.8: 29.03
+	Hs
		1080880 HSPB2_HUMAN (1-181): 2.16e-45: 150: 35.52		AGA11_HUMAN (567-697): 5.11e-14: 77.6: 25.37