Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: KPCD1 (Q15139)
Serine/threonine-protein kinase D1 (EC 2.7.11.13) (Protein kinase C mu type) (Protein kinase D) (nPKC-D1) (nPKC-mu)
Gene: PRKD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 15728188, 31980649, 18440775, unassigned2173
Identification Methods pull down, affinity chromatography technology, enzymatic study, in-gel kinase assay, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005080 - protein kinase C binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0030018 - Z disc
GO:0035556 - intracellular signal transduction
and 5 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 205
Hs

1 912
+ Hs
+ Mm
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+ Mm
+ Hs
+ Mm
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+ Mm

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Last updated: 15 Jul 2024