HitPredict

Interactor 1: HSPB1 (P04792)
Heat shock protein beta-1 (HspB1) (28 kDa heat shock protein) (Estrogen-regulated 24 kDa protein) (Heat shock 27 kDa protein) (HSP 27) (Heat shock protein family B member 1) (Stress-responsive protein 27) (SRP27)
Gene: HSPB1

Interactor 2: CHIP (Q9UNE7)
E3 ubiquitin-protein ligase CHIP (EC 2.3.2.27) (Antigen NY-CO-7) (CLL-associated antigen KW-8) (Carboxy terminus of Hsp70-interacting protein) (RING-type E3 ubiquitin transferase CHIP) (STIP1 homology and U box-containing protein 1)
Gene: STUB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	25277244, 32814053
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid pooling approach, reverse ras recruitment system
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030018 - Z disc GO:0042803 - protein homodimerization activity
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 303
+	Hs
		297021 HSPB1_HUMAN (1-205): 4.5e-80: 239: 100.00		TOM70_HUMAN (4-212): 8.69e-40: 148: 22.47