HitPredict

Interactor 1: DNLI1 (P04819)
DNA ligase 1 (EC 6.5.1.1) (DNA ligase I) (Polydeoxyribonucleotide synthase [ATP] 1)
Gene: CDC9

Interactor 2: PCNA (P15873)
Proliferating cell nuclear antigen (PCNA)
Gene: POL30

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 0.60 0.731

The method score is based on:

Property Details
Experiments 20967232, 11805837, 17308348, 16079237, 26212319, 22308326
Identification Methods two hybrid, anti tag coimmunoprecipitation, x-ray crystallography, pull down, affinity chromatography technology
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000278 - mitotic cell cycle
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006273 - lagging strand elongation
GO:0006289 - nucleotide-excision repair
and 1 others

more...
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 755
Sc

1 258
+ Hs
+ Sp
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024