HitPredict

Interactor 1: CY24B (P04839)
Cytochrome b-245 heavy chain (EC 1.-.-.-) (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Heme-binding membrane glycoprotein gp91phox) (NADPH oxidase 2) (Neutrophil cytochrome b 91 kDa polypeptide) (Superoxide-generating NADPH oxidase heavy chain subunit) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome)
Gene: CYBB

Interactor 2: IRF1 (P10914)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.585

Property	Details
Experiments	11781315, 9593745, 8798551
Identification Methods	electrophoretic mobility supershift assay, electrophoretic mobility shift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 570 Hs			1 325
+	Hs
		389785 CY24B_HUMAN (1-570): 0: 672: 100.00		IRF8_HUMAN (7-270): 1.22e-99: 301: 28.79
+	Mm
		618962 CY24B_MOUSE (1-570): 0: 671: 93.16		IRF8_MOUSE (7-270): 2.81e-94: 287: 28.03
+	Hs
		389772 CY24B_HUMAN (1-570): 0: 672: 100.00		IRF2_HUMAN (1-268): 2.01e-86: 265: 45.55