HitPredict

Interactor 1: CY24B (P04839)
Cytochrome b-245 heavy chain (EC 1.-.-.-) (CGD91-phox) (Cytochrome b(558) subunit beta) (Cytochrome b558 subunit beta) (Heme-binding membrane glycoprotein gp91phox) (NADPH oxidase 2) (Neutrophil cytochrome b 91 kDa polypeptide) (Superoxide-generating NADPH oxidase heavy chain subunit) (gp91-1) (gp91-phox) (p22 phagocyte B-cytochrome)
Gene: CYBB

Interactor 2: IRF8 (Q02556)
Interferon regulatory factor 8 (IRF-8) (Interferon consensus sequence-binding protein) (H-ICSBP) (ICSBP)
Gene: IRF8

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.50	0.617

Property	Details
Experiments	9593745, 15371411, 18089853, 15496449
Identification Methods	electrophoretic mobility shift assay, anti tag coimmunoprecipitation, electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 570 Hs			1 426
+	Mm
		618962 CY24B_MOUSE (1-570): 0: 671: 93.16		IRF8_MOUSE (1-426): 0: 579: 89.67
+	Hs
		389770 CY24B_HUMAN (1-570): 0: 672: 100.00		IRF1_HUMAN (9-187): 2.59e-62: 206: 33.69
+	Hs
		389772 CY24B_HUMAN (1-570): 0: 672: 100.00		IRF2_HUMAN (9-167): 4.69e-53: 182: 36.88