HitPredict

Interactor 1: RPN1 (P04843)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1)
Gene: RPN1

Interactor 2: STT3A (P46977)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A (Oligosaccharyl transferase subunit STT3A) (STT3-A) (EC 2.4.99.18) (B5) (Integral membrane protein 1) (Transmembrane protein TMC)
Gene: STT3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.940

Property	Details
Experiments	35271311, 30021884, 32788342, 34079125, 35235311, 37071682
Identification Methods	affinity chromatography technology, proximity labelling technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ribophorin_I~STT3
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0006487 - protein N-linked glycosylation GO:0008250 - oligosaccharyltransferase complex GO:0016020 - membrane GO:0018279 - protein N-linked glycosylation via asparagine
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 705
+	Hs
		390395 RPN1_HUMAN (1-607): 0: 897: 100.00		STT3B_HUMAN (15-700): 0: 1100: 59.41
+	Sc
		759060 OST1_YEAST (23-464): 2.89e-149: 441: 26.98		STT3_YEAST (15-701): 0: 954: 54.05