HitPredict

Interactor 1: RPN2 (P04844)
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2)
Gene: RPN2

Interactor 2: INSR (P06213)
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor subunit alpha; Insulin receptor subunit beta]
Gene: INSR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 631 Hs			1 1382
+	Rn
		544778 RPN2_RAT (1-631): 0: 852: 93.82		INSR_RAT (1-1382): 0: 1527: 94.44
+	Hs
		390664 RPN2_HUMAN (1-631): 0: 877: 100.00		IGF1R_HUMAN (31-1380): 0: 1353: 56.11
+	Hs
		390724 RPN2_HUMAN (1-631): 0: 877: 100.00		EPHA8_HUMAN (644-1322): 3.66e-168: 531: 20.68
+	Hs
		390725 RPN2_HUMAN (1-631): 0: 877: 100.00		LTK_HUMAN (1013-1291): 2e-71: 259: 44.52
+	Hs
		384080 RPN2_HUMAN (1-631): 0: 877: 100.00		NTRK1_HUMAN (996-1286): 9.16e-68: 247: 42.62
+	Hs
		390913 RPN2_HUMAN (1-631): 0: 877: 100.00		NTRK3_HUMAN (996-1290): 1.93e-64: 238: 39.43
+	Hs
		390728 RPN2_HUMAN (1-631): 0: 877: 100.00		UFO_HUMAN (789-1294): 1.77e-61: 229: 31.09